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Active Pharmaceutical 98% Pizotifen For Antimigraine CAS 15574-96-6

Categories Pharmaceutical Raw Materials
Brand Name: JNJG
Model Number: 15574-96-6
Certification: USP BP SGS KOSHER
Place of Origin: CHINA
MOQ: Negotiable
Price: negotiation
Payment Terms: TT, Money Gram, Western Union, Bitcoin
Supply Ability: 500kg/per week
Delivery Time: within 12 hours after you payment
Packaging Details: 1kg/ foil bag or as your requirement
CAS: 15574-96-6
MF: C19H21NS
MW: 295.44
Melting Point: 140-142°C
Density: 1.164g/cm3
Boiling point: 436.7°C at 760 mmHg
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    Active Pharmaceutical 98% Pizotifen For Antimigraine CAS 15574-96-6

    Active Pharmaceutical 98% Pizotifen For Antimigraine CAS 15574-96-6


    Quick Detail

    Product Name

    Pizotifen


    Synonym

    Pizotylene;Pizothifenum;Pizotifenum;Pizotyline (base and/or unspecified salts);4-OXO-9,10-DIHYDRO-4H-BENZO(4,5) Cyclohepto(1,2,B) Thiophene;PIZOTIFEN;4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine;


    CAS

    15574-96-6


    MF

    C19H21NS


    MW

    295.44

    EINECS

    239-632-9


    Purity

    99%


    Appearance

    White Powder


    Melting Point

    140-142°C


    Boiling Point

    436.7°C at 760 mmHg


    Density

    1.164g/cm3


    Refractive index

    1.63

    Flash point

    217.9°C

    Vapour Pressur

    7.92E-08mmHg at 25°C

    Usage

    Serotonin antagonist structurally related to Cyproheptadine. Antimigraine;appetite stimulant.



    Description


    Pizotifen called new degree Semillon, pizotifen malate, is a chemical synthetic antihistamines, its chemical structure is similar cyproheptadine and amitriptyline, has strong anti 5- serotonin and histamine and weak anti acetylcholine effect, one of the commonly used drugs for the prevention of migraine.


    1. This product is inhibition of bradykinin (BK) on the peripheral nerve pain induced sedation, and antidepressant effect.


    2. This product can reduce the ethanol tolerance,can strengthen the tranquilizer, sedative and tricyclic

    antidepressant effect.


    Clinical mainly for typical and atypical migraine, can relieve a symptom, reduce seizure frequency and duration, obvious curative effect on acute migraine, but no immediate relief, also be tried in erythromelalgia, angioneurotic edema, chronic urticaria, skin Nick disease etc.. Another report, pizotifen for carcinoid syndrome caused by diarrhea and flushing,carotid pain, polycythemia induced pruritus.



    Pizotifen Use


    The main medical use for pizotifen is for the prevention of vascular headache including migraine and cluster headache. Pizotifen is one of a range of medications used for this purpose, other options include propranolol, topiramate, valproic acid and amitriptyline. While pizotifen is reasonably effective, its use is limited by side effects, principally drowsiness and weight gain, and it is usually not the first choice medicine for preventing migraines, instead being used as an alternative when other drugs have failed to be effective. It is not effective in relieving migraine attacks once in progress. Pizotifen has also been reported as highly effective in a severe case of erythromelalgia, a rare neurovascular disease that is sometimes refractory to the other drugs named above.


    Other applications for which pizotifen may be used include as an antidepressant, or for the treatment of anxiety or social phobia. Animal studies also suggest that pizotyline could be used in the treatment of serotonin syndrome or MDMA overdose in a similar manner to the closely related antihistamine/ antiserotonin drug cyproheptadine.


    How does this medication work? What will it do for me?

    Pizotifen is used to prevent migraine headaches. It is not used to treat headaches once they have started. It is not known exactly how this medication works, but it is thought to affect chemicals, called neurotransmitters, in the brain. It may take up to 4 weeks for the medication to have its maximum effect.

    This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.


    Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

    Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.


    Advantage:


    1, High quality with competitive price:
    1) Standard:Enterprise Standard
    2) All Purity≥98%
    3) We are manufacturer and can provide high quality products with factory price.


    2, Fast and safe delivery
    1) Parcel can be sent out within 24 hours after payment.Tracking number available
    2) Secure and discreet shipment.Various transportation methods for your choice.
    3) Customs pass rate ≥99%
    4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.


    3, We have clients throughout the world.
    1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
    2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
    3) High quality,competitive price, fast delivery, first-class service gain the trust and praise from the customers.


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